Gleason Score 6 Adenocarcinoma: Should It Be Labeled As Cancer?
نویسندگان
چکیده
منابع مشابه
Gleason score 6 adenocarcinoma: should it be labeled as cancer?
Overtreatment of low-grade prostate cancer (Gleason score 6) is a recognized problem today, with systematic prostate gland sampling triggered by prostate-specific antigen (PSA) measurements. The extent to which overtreatment is caused by fear of death resulting from cancer, fear of litigation from undertreatment, and misaligned incentives that reimburse more for treating rather than monitoring ...
متن کاملGleason Score 6 - Prostate Cancer or Benign Variant?
The leading motivation behind wanting to call a 'malignant' prostate lesion 'benign' is the evidence of indolent prostate cancer that is not associated with a fatal outcome and in part makes therapeutic measures such as surgery and radiotherapy appear like overtreatment for some or possibly the majority of such patients. The present article reviews the definitions of 'precancerous lesion' and '...
متن کاملShould we really consider Gleason 6 prostate cancer?
Taunton, UK There is no doubt that prostate cancer kills, but only a minority of men who are given this diagnosis, die from prostate cancer. In the developed world we are now overdiagnosing and, more importantly, overtreating prostate cancer, a fact for which we will be criticized in generations to come. As well-intentioned urologists, we should have no trouble in justifying our radical therapy...
متن کاملDoes prostate acinar adenocarcinoma with Gleason Score 3 + 3 = 6 have the potential to metastasize?
BACKGROUND There is a worldwide debate involving clinicians, uropathologists as well as patients and their families on whether Gleason score 6 adenocarcinoma should be labelled as cancer. CASE DESCRIPTION We report a case of man diagnosed with biopsy Gleason score 6 acinar adenocarcinoma and classified as low risk (based on a PSA of 5 ng/mL and stage cT2a) whose radical prostatectomy specimen...
متن کاملShould we replace the Gleason score with the amount of high-grade prostate cancer?
OBJECTIVES The stage and grade shift of currently diagnosed prostate cancer has led to a diminished prognostic power of the Gleason score system. We investigated the predictive value of the amount of high-grade cancer (Gleason growth patterns 4/5) in the biopsy for prostate-specific antigen (PSA) and clinical relapse after radical prostatectomy. METHODS PSA-tested participants (N=281) of the ...
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ژورنال
عنوان ژورنال: Journal of Clinical Oncology
سال: 2012
ISSN: 0732-183X,1527-7755
DOI: 10.1200/jco.2012.44.0586